[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid diethyl ester(A3)
[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid diethyl ester
CAS: 116384-53-3
Molecular Formula: C12H20N5O4P
[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid diethyl ester(A3) - Names and Identifiers
| Name | [[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid diethyl ester |
| Synonyms | Adefovir Dipivoxil InterMediates 9-[2-(DIETHYLPHOSPHONOMETHOXY)ETHYL]ADENINE 9-[2-(diethoxyphosphorylmethoxy)ethyl]purin-6-amine 9-[2-(Diethylphosphonomethoxy)ethyl]adenine(Diethyl PMEA) 9-[2-(diethylphosphonomethoxy)ethyl]adenine phosphonic acid Diethyl [[2-(6-AMino-9H-purin-9-yl)ethoxy]Methyl]phosphonate Diethyl [[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonate 9-[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]phosphonicaciddiethylester [[2-(6-AMINO-9H-PURIN-9-YL)ETHOXY]METHYL]PHOSPHONIC ACID DIETHYL ESTER [[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid diethyl ester [[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid diethyl ester(A3) |
| CAS | 116384-53-3 |
| EINECS | 601-426-5 |
| InChI | InChI=1/C12H20N5O4P/c1-3-20-22(18,21-4-2)9-19-6-5-17-8-16-10-11(13)14-7-15-12(10)17/h7-8H,3-6,9H2,1-2H3,(H2,13,14,15) |
| InChIKey | SACBMARVYGBCAK-UHFFFAOYSA-N |
[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid diethyl ester(A3) - Physico-chemical Properties
| Molecular Formula | C12H20N5O4P |
| Molar Mass | 329.29 |
| Density | 1.45±0.1 g/cm3(Predicted) |
| Melting Point | 134.0 to 138.0 °C |
| Boling Point | 531.1±60.0 °C(Predicted) |
| Flash Point | 275°C |
| Vapor Presure | 2.32E-11mmHg at 25°C |
| pKa | 4.18±0.10(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.619 |
[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid diethyl ester(A3) - Introduction
Diethyl [[2-(6-amino-9H-purin-9-yl) ethoxy] methyl] phosphonate, also known as AMPP-EE, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: colorless liquid
-Molecular formula: C14H19N5O6P
-Molecular weight: 413.30g/mol
-Solubility: Soluble in organic solvents such as ethanol and chloroform
Use:
- [2-(6-amino-9H-purin-9-yl) ethoxy] methyl phosphonic acid diethyl ester is commonly used as an important intermediate in the field of biomedicine, and can be used for the synthesis of anti-tumor, anti-virus and anti-inflammatory drugs.
Method:
Diethyl- [2-(6-amino-9H-purin-9-yl) ethoxy] methylphosphonate is typically prepared by chemical synthetic methods. Specific steps involve the use of reaction conditions and catalysts, as well as a series of reaction processes. These methods are generally used only in laboratories or in industry.
Safety Information:
- [2-(6-amino-9H-purin-9-yl) ethoxy] methyl phosphonic acid diethyl ester needs to be safe during use and storage. It can be irritating to the eyes and skin, so wear appropriate personal protective equipment. Avoid inhalation or contact and seek medical advice immediately if maladjustment occurs. In the process of use, should follow the relevant chemical safety procedures.
Nature:
-Appearance: colorless liquid
-Molecular formula: C14H19N5O6P
-Molecular weight: 413.30g/mol
-Solubility: Soluble in organic solvents such as ethanol and chloroform
Use:
- [2-(6-amino-9H-purin-9-yl) ethoxy] methyl phosphonic acid diethyl ester is commonly used as an important intermediate in the field of biomedicine, and can be used for the synthesis of anti-tumor, anti-virus and anti-inflammatory drugs.
Method:
Diethyl- [2-(6-amino-9H-purin-9-yl) ethoxy] methylphosphonate is typically prepared by chemical synthetic methods. Specific steps involve the use of reaction conditions and catalysts, as well as a series of reaction processes. These methods are generally used only in laboratories or in industry.
Safety Information:
- [2-(6-amino-9H-purin-9-yl) ethoxy] methyl phosphonic acid diethyl ester needs to be safe during use and storage. It can be irritating to the eyes and skin, so wear appropriate personal protective equipment. Avoid inhalation or contact and seek medical advice immediately if maladjustment occurs. In the process of use, should follow the relevant chemical safety procedures.
Last Update：2024-04-09 20:49:11
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Product Name: [[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid diethyl ester Request for quotation
CAS: 116384-53-3
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CAS: 116384-53-3
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